lab of action
Scott Grafton Gene Tunik Antonia Hamilton Nichola Rice Stephanie Ortigue
Emily Cross Nick Wymbs


Cross, E. S., Hamilton, A. F. de C., & Grafton, S. T. (in press) Building a simulation de novo: Observation of dance by dancersNeuroimage.

Hamilton AF, Grafton ST. Goal representation in human anterior intraparietal sulcus. J Neurosci. 2006 Jan 25;26(4):1133-7.

Van Horn JD, Yanos M, Schmitt PJ, Grafton ST. Alcohol-induced suppression of BOLD activity during goal-directed visuomotor performance.  Neuroimage. 2006 Mar 7;

Hamilton AF, Wolpert DM, Frith U, Grafton ST  Where does your own action influence your perception of another person's action in the brain? Neuroimage. 2006 Jan 15;29(2):524-35.

Hynes CA, Baird AA, Grafton ST.       Differential role of the orbital frontal lobe in emotional versus cognitive perspective-taking.  Neuropsychologia. 2006;44(3):374-83.


Desmurget M, Turner RS, Prablanc C, Russo GS, Alexander GE, Grafton ST. Updating target location at the end of an orienting saccade affects the characteristics of simple point-to-point movements. J Exp Psychol Hum Percept Perform. 2005 Dec;31(6):1510-36.

Wig GS, Grafton ST, Demos KE, Kelley WM. Reductions in neural activity underlie behavioral components of repetition priming.  Nat Neurosci. 2005 Sep;8(9):1228-33.

Handy TC, Schaich Borg J, Turk DJ, Tipper CM, Grafton ST, Gazzaniga MS.   Placing a tool in the spotlight: spatial attention modulates visuomotor responses in cortex. Neuroimage. 2005 May 15;26(1):266-76.

Tunik E, Frey SH, Grafton ST. Virtual lesions of the anterior intraparietal area disrupt goal-dependent on-line adjustments of grasp.Nature Neuroscience 2005 Apr;8(4):505-11

Handy TC, Schaich Borg J, Turk DJ, Tipper CM, Grafton ST, Gazzaniga MS.     Placing a tool in the spotlight: spatial attention modulates visuomotor responses in cortex. Neuroimage. 2005 May 15;26(1):266-76.  

Frey SH, Vinton D, Norlund R, Grafton ST .     Cortical topography of human anterior intraparietal cortex active during visually guided grasping. Brain Res Cogn Brain Res. 2005 May;23(2-3):397-405.


Review    Grafton ST .     Contributions of functional imaging to understanding parkinsonian symptoms. Curr Opin Neurobiol. 2004 Dec;14(6):715-9

Schweitzer JB, Lee DO, Hanford RB, Zink CF, Ely TD, Tagamets MA, Hoffman JM, Grafton ST, Kilts CD.     Effect of methylphenidate on executive functioning in adults with attention-deficit/hyperactivity disorder: normalization of behavior but not related brain activity. Biol Psychiatry. 2004 Oct 15;56(8):597-606.  

Johnson-Frey SH, Newman-Norlund R, Grafton ST.     A Distributed Left Hemisphere Network Active During Planning of Everyday Tool Use Skills. Cereb Cortex. 2004 Sep 1;   

Grafton ST .   Doing more with less: the plight of the failing hippocampus. Ann Neurol. 2004 Jul;56(1):7-9.   

Turk DJ, Banfield JF, Walling BR, Heatherton TF, Grafton ST, Handy TC, Gazzaniga MS, Macrae CN.     From facial cue to dinner for two: the neural substrates of personal choice. Neuroimage. 2004 Jul;22(3):1281-90.  

Desmurget M, Grafton ST , Vindras P, Grea H, Turner RS.     The basal ganglia network mediates the planning of movement amplitude. Eur J Neurosci. 2004 May;19(10):2871-80.  

Review  Van Horn JD, Grafton ST , Rockmore D, Gazzaniga MS.     Sharing neuroimaging studies of human cognition. Nat Neurosci. 2004 May;7(5):473-81.

Bischoff-Grethe A, Goedert KM, Willingham DT, Grafton ST.     Neural substrates of response-based sequence learning using fMRI. J Cogn Neurosci. 2004 Jan-Feb;16(1):127-38.  

Leslie KR, Johnson-Frey SH, Grafton ST .     Functional imaging of face and hand imitation: towards a motor theory of empathy. Neuroimage. 2004 Feb;21(2):601-7.  


Desmurget M, Grafton ST , Vindras P, Grea H, Turner RS.     Basal ganglia network mediates the control of movement amplitude. Exp Brain Res. 2003 Nov;153(2):197-209.

Johnson-Frey SH, Maloof FR, Newman-Norlund R, Farrer C, Inati S, Grafton ST .     Actions or hand-object interactions? Human inferior frontal cortex and action observation. Neuron. 2003 Sep 11;39(6):1053-8.  

Turner RS, Desmurget M, Grethe J, Crutcher MD, Grafton ST.   Motor subcircuits mediating the control of movement extent and speed. J Neurophysiol. 2003 Dec;90(6):3958-66.

Review  Janata P, Grafton ST .     Swinging in the brain: shared neural substrates for behaviors related to sequencing and music. Nat Neurosci. 2003 Jul;6(7):682-7.

Davis MR, Votaw JR, Bremner JD, Byas-Smith MG, Faber TL, Voll RJ, Hoffman JM, Grafton ST, Kilts CD, Goodman MM.     Initial human PET imaging studies with the dopamine transporter ligand 18F-FECNT. J Nucl Med. 2003 Jun;44(6):855-61.  

Turner RS, Grafton ST , McIntosh AR , DeLong MR, Hoffman JM.     The functional anatomy of parkinsonian bradykinesia. Neuroimage. 2003 May;19(1):163-79.  

Schweitzer JB, Lee DO, Hanford RB, Tagamets MA, Hoffman JM, Grafton ST , Kilts CD.     A positron emission tomography study of methylphenidate in adults with ADHD: alterations in resting blood flow and predicting treatment response. Neuropsychopharmacology. 2003 May;28(5):967-73.

Review   Johnson SH, Grafton ST .     From 'acting on' to 'acting with': the functional anatomy of object-oriented action schemata. Prog Brain Res. 2003;142:127-39..  

Handy TC, Grafton ST , Shroff NM , Ketay S, Gazzaniga MS.     Graspable objects grab attention when the potential for action is recognized. Nat Neurosci. 2003 Apr;6(4):421-7.  


Johnson SH, Rotte M, Grafton ST , Hinrichs H, Gazzaniga MS, Heinze HJ.     Selective activation of a parietofrontal circuit during implicitly imagined prehension. Neuroimage. 2002 Dec;17(4):1693-704.  

Grafton ST , Hazeltine E, Ivry RB.     Motor sequence learning with the nondominant left hand. A PET functional imaging study. Exp Brain Res. 2002 Oct;146(3):369-78. Epub 2002 Aug 24.  

Bischoff-Grethe A, Ivry RB, Grafton ST.   Cerebellar involvement in response reassignment rather than attention. J Neurosci. 2002 Jan 15;22(2):546-53.  


Corballis PM, Inati S, Funnell MG, Grafton ST , Gazzaniga MS.    MRI assessment of spared fibers following callosotomy: a second look. Neurology. 2001 Oct 9;57(7):1345-6..  

Desmurget M, Grea H, Grethe JS, Prablanc C, Alexander GE, Grafton ST.   Functional anatomy of nonvisual feedback loops during reaching: a positron emission tomography study. J Neurosci. 2001 Apr 15;21(8):2919-28.  

Grafton ST , Salidis J, Willingham DB.     Motor learning of compatible and incompatible visuomotor maps. J Cogn Neurosci. 2001 Feb 15;13(2):217-31.  


Desmurget M, Vindras P, Grea H, Viviani P, Grafton ST.     Proprioception does not quickly drift during visual occlusion. Exp Brain Res. 2000 Oct;134(3):363-77.  

Review Grafton ST .     PET: activation of cerebral blood flow and glucose metabolism. Adv Neurol. 2000;83:87-103.  

Desmurget M, Pelisson D, Grethe JS, Alexander GE, Urquizar C, Prablanc C, Grafton ST .     Functional adaptation of reactive saccades in humans: a PET study. Exp Brain Res. 2000 May;132(2):243-59.  

Schweitzer JB, Faber TL, Grafton ST, Tune LE, Hoffman JM, Kilts CD.   Alterations in the functional anatomy of working memory in adult attention deficit hyperactivity disorder. Am J Psychiatry. 2000 Feb;157(2):278-80.  


Zangaladze A, Epstein CM, Grafton ST , Sathian K.     Involvement of visual cortex in tactile discrimination of orientation. Nature. 1999 Oct 7;401(6753):587-90.  

Conti PS, Durski JM, Bacqai F, Grafton ST, Singer PA.     Imaging of locally recurrent and metastatic thyroid cancer with positron emission tomography. Thyroid. 1999 Aug;9(8):797-804.  

Desmurget M, Epstein CM, Turner RS, Prablanc C, Alexander GE, Grafton ST.     Role of the posterior parietal cortex in updating reaching movements to a visual target. Nat Neurosci. 1999 Jun;2(6):563-7.  

Halkar RK, Toro JR, Lim EH, Staley CA, Grafton ST, Garcia EV, Hoffman J.   Role of FDG-PET in the Pre-Operative Evaluation of Surgical Resection of Hepatic Metastases from Colorectal Cancer. Clin Positron Imaging. 1999 Nov;2(6):335.   

Henry TR, Votaw JR, Pennell PB, Epstein CM, Bakay RA, Faber TL, Grafton ST, Hoffman JM.     Acute blood flow changes and efficacy of vagus nerve stimulation in partial epilepsy. Neurology. 1999 Apr 12;52(6):1166-73.  

Hamann SB, Ely TD, Grafton ST , Kilts CD.     Amygdala activity related to enhanced memory for pleasant and aversive stimuli. Nat Neurosci. 1999 Mar;2(3):289-93.  

Sathian K, Simon TJ, Peterson S, Patel GA, Hoffman JM, Grafton ST.     Neural evidence linking visual object enumeration and attention. J Cogn Neurosci. 1999 Jan;11(1):36-51.  


Desmurget M, Pelisson D, Urquizar C, Prablanc C, Alexander GE, Grafton ST.     Functional anatomy of saccadic adaptation in humans. Nat Neurosci. 1998 Oct;1(6):524-8. Erratum in: Nat Neurosci 1998 Dec;1(8):743.  

Woodard JL, Grafton ST, Votaw JR, Green RC, Dobraski ME, Hoffman JM.     Compensatory recruitment of neural resources during overt rehearsal of word lists in Alzheimer's disease. Neuropsychology. 1998 Oct;12(4):491-504.  

Grafton ST , Hazeltine E, Ivry RB.   Abstract and effector-specific representations of motor sequences identified with PET. J Neurosci. 1998 Nov 15;18(22):9420-8.  

Turner RS, Grafton ST , Votaw JR, Delong MR, Hoffman JM.   Motor subcircuits mediating the control of movement velocity: a PET study. J Neurophysiol. 1998 Oct;80(4):2162-76.  

Henry TR, Bakay RA, Votaw JR, Pennell PB, Epstein CM, Faber TL, Grafton ST, Hoffman JM.     Brain blood flow alterations induced by therapeutic vagus nerve stimulation in partial epilepsy: I. Acute effects at high and low levels of stimulation. Epilepsia. 1998 Sep;39(9):983-90.  

Grafton ST , Fagg AH, Arbib MA.   Dorsal premotor cortex and conditional movement selection: A PET functional mapping study. J Neurophysiol. 1998 Feb;79(2):1092-7.  

Woods RP, Grafton ST, Watson JD, Sicotte NL, Mazziotta JC.     Automated image registration: II. Intersubject validation of linear and nonlinear models. J Comput Assist Tomogr. 1998 Jan-Feb;22(1):153-65.  

Woods RP, Grafton ST , Holmes CJ, Cherry SR, Mazziotta JC.     Automated image registration: I. General methods and intrasubject, intramodality validation. J Comput Assist Tomogr. 1998 Jan-Feb;22(1):139-52.  


Sathian K, Zangaladze A, Hoffman JM, Grafton ST .     Feeling with the mind's eye. Neuroreport. 1997 Dec 22;8(18):3877-81.  

Grafton ST , Fadiga L, Arbib MA, Rizzolatti G.     Premotor cortex activation during observation and naming of familiar tools. Neuroimage. 1997 Nov;6(4):231-6.  

Grafton ST, DeLong M.    Tracing the brain's circuitry with functional imaging. Nat Med. 1997 Jun;3(6):602-3.   

Winstein CJ, Grafton ST, Pohl PS.    Motor task difficulty and brain activity: investigation of goal-directed reciprocal aiming using positron emission tomography. J Neurophysiol. 1997 Mar;77(3):1581-94.  

Hazeltine E, Grafton ST , Ivry R.    Attention and stimulus characteristics determine the locus of motor-sequence encoding. A PET study. Brain. 1997 Jan;120 ( Pt 1):123-40.  


Grafton ST , Arbib MA, Fadiga L, Rizzolatti G.     Localization of grasp representations in humans by positron emission tomography. 2. Observation compared with imagination. Exp Brain Res. 1996 Nov;112(1):103-11.  

Conti PS, Lilien DL, Hawley K, Keppler J, Grafton ST, Bading JR.     PET and [18F]-FDG in oncology: a clinical update. Nucl Med Biol. 1996 Aug;23(6):717-35. Review.  

Grafton ST , Fagg AH, Woods RP, Arbib MA.     Functional anatomy of pointing and grasping in humans. Cereb Cortex. 1996 Mar-Apr;6(2):226-37.  

1995 and earlier

Couldwell WT, Grafton ST .   Pallidotomy in advanced Parkinson's disease. Neurosurgery. 1995 Dec;37(6):1234  

Logan CG, Grafton ST .   Functional anatomy of human eyeblink conditioning determined with regional cerebral glucose metabolism and positron-emission tomography. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7500-4.  

Grafton ST, Waters C, Sutton J, Lew MF, Couldwell W.     Pallidotomy increases activity of motor association cortex in Parkinson's disease: a positron emission tomographic study. Ann Neurol. 1995 Jun;37(6):776-83.  

Victoroff J, Mack WJ, Grafton ST , Schreiber SS, Chui HC.     A method to improve interrater reliability of visual inspection of brain MRI scans in dementia. Neurology. 1994 Dec;44(12):2267-76.  

Hoffman JM, Lee A, Grafton ST, Bellamy P, Hawkins RA, Webber M.     Clinical signs and symptoms in pulmonary embolism. A reassessment. Clin Nucl Med. 1994 Sep;19(9):803-8.  

Grafton ST .   Cortical control of movement. Ann Neurol. 1994 Jul;36(1):3-4.   

Tyszka JM, Grafton ST, Chew W, Woods RP, Colletti PM.     Parceling of mesial frontal motor areas during ideation and movement using functional magnetic resonance imaging at 1.5 tesla. Ann Neurol. 1994 Jun;35(6):746-9.  

Grafton ST, Martin NA, Mazziotta JC, Woods RP, Vinuela F, Phelps ME.     Localization of motor areas adjacent to arteriovenous malformations. A positron emission tomographic study. J Neuroimaging. 1994 Apr;4(2):97-103.  

Victoroff JI, Benson F, Grafton ST , Engel J Jr, Mazziotta JC.     Depression in complex partial seizures. Electroencephalography and cerebral metabolic correlates. Arch Neurol. 1994 Feb;51(2):155-63.  

Llacer J, Veklerov E, Baxter LR, Grafton ST, Griffeth LK, Hawkins RA, Hoh CK, Mazziotta JC, Hoffman EJ, Metz CE.     Results of a clinical receiver operating characteristic study comparing filtered backprojection and maximum likelihood estimator images in FDG PET studies. J Nucl Med. 1993 Jul;34(7):1198-203.  

Yu DC, Huang SC, Grafton ST, Melega WP, Barrio JR, Mazziotta JC, Phelps ME.     Methods for improving quantitation of putamen uptake constant of FDOPA in PET studies. J Nucl Med. 1993 Apr;34(4):679-88.  

Grafton ST , Woods RP, Mazziotta JC.     Within-arm somatotopy in human motor areas determined by positron emission tomography imaging of cerebral blood flow. Exp Brain Res. 1993;95(1):172-6.  

Grafton ST, Mazziotta JC, Pahl JJ, St George-Hyslop P, Haines JL, Gusella J, Hoffman JM, Baxter LR, Phelps ME.     Serial changes of cerebral glucose metabolism and caudate size in persons at risk for Huntington's disease. Arch Neurol. 1992 Nov;49(11):1161-7.  

Grafton ST , Mazziotta JC, Presty S, Friston KJ, Frackowiak RS, Phelps ME.     Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET. J Neurosci. 1992 Jul;12(7):2542-8.  

Grafton ST, Mazziotta JC, Woods RP, Phelps ME.     Human functional anatomy of visually guided finger movements. Brain. 1992 Apr;115 ( Pt 2):565-87.  

Baxter LR Jr, Mazziotta JC, Pahl JJ, Grafton ST, St George-Hyslop P, Haines JL, Gusella JF, Szuba MP, Selin CE, Guze BH, et al.     Psychiatric, genetic, and positron emission tomographic evaluation of persons at risk for Huntington's disease. Arch Gen Psychiatry. 1992 Feb;49(2):148-54.   

Melega WP, Grafton ST, Huang SC, Satyamurthy N, Phelps ME, Barrio JR.     L-6-[18F]fluoro-dopa metabolism in monkeys and humans: biochemical parameters for the formulation of tracer kinetic models with positron emission tomography. J Cereb Blood Flow Metab. 1991 Nov;11(6):890-7.  

Grafton ST, Woods RP, Mazziotta JC, Phelps ME.     Somatotopic mapping of the primary motor cortex in humans: activation studies with cerebral blood flow and positron emission tomography. J Neurophysiol. 1991 Sep;66(3):735-43.  

Grafton ST, Sumi SM, Stimac GK, Alvord EC Jr, Shaw CM, Nochlin D.     Comparison of postmortem magnetic resonance imaging and neuropathologic findings in the cerebral white matter. Arch Neurol. 1991 Mar;48(3):293-8.  

Grafton ST, Mazziotta JC, Pahl JJ, St George-Hyslop P, Haines JL, Gusella J, Hoffman JM, Baxter LR, Phelps ME.     A comparison of neurological, metabolic, structural, and genetic evaluations in persons at risk for Huntington's disease. Ann Neurol. 1990 Nov;28(5):614-21.  

Freed CR, Breeze RE, Rosenberg NL, Schneck SA, Wells TH, Barrett JN, Grafton ST , Huang SC , Eidelberg D, Rottenberg DA.     Transplantation of human fetal dopamine cells for Parkinson's disease. Results at 1 year. Arch Neurol. 1990 May;47(5):505-12.  

Freed CR, Breeze RE, Rosenberg NL, Schneck SA, Wells TH, Barrett JN, Grafton ST, Mazziotta JC, Eidelberg D, Rottenberg DA.   Therapeutic effects of human fetal dopamine cells transplanted in a patient with Parkinson's disease. Prog Brain Res. 1990;82:715-21. No  available.  

Melega WP, Perlmutter MM, Luxen A, Nissenson CH, Grafton ST, Huang SC, Phelps ME, Barrio JR.     4-[18F]fluoro-L-m-tyrosine: an L-3,4-dihydroxyphenylalanine analog for probing presynaptic dopaminergic function with positron emission tomography. J Neurochem. 1989 Jul;53(1):311-4.  

Grafton ST , Bahls FH, Bell KR.   Acquired focal dystonia following recovery from central pontine myelinolysis. J Neurol Neurosurg Psychiatry. 1988 Oct;51(10):1354-5  

Grafton ST , Longstreth WT Jr.     Steroids after cardiac arrest: a retrospective study with concurrent, nonrandomized controls. Neurology. 1988 Aug;38(8):1315-6.  

Website created by Antonia Hamilton. Last updated 12 November 2005.